Shortcomings in risk projection.

Shortcomings in risk projection.

-Gonadotrophins, oestradiol, androstenedione, testosterone and dehydroepiandrosterone sulphate (DHAS) were measured sequentially in 72 patients with advanced breast cancer receiving endocrine therapy of various types. Tamoxifen significantly reduced gonadotrophins but did not effect other hormones. Danazol also reduced gonadotrophins. Aminoglutethimide (AGT) reduced oestradiol and DHAS but had ...

A flood risk projection for Soleimantangeh Dam against future climate change

A sensitivity analysis of the flood safety of Solaimantangeh dam using a regional climate change simulation is presented. Based on the output of the CCSM (Community Climate Change System Model) general circulation model, the NIRCM (North of Iran Regional Climate Model) computes regional scale output with 50 km spatial resolution and 21 vertical layers. Using the SRES (Special Report Emission Sc...

Uncertainty in asset correlation for portfolio credit risk: the shortcomings of the Basel II framework

Moody’s databases of corporate issuers of long term bonds and structured products are used to estimate asset correlations across a group of sectors, world regions and products. The estimation of a dynamic factor model for default risk is performed using Bayesian methods. Results indicate that a two factor model rather than the one factor model, as proposed by the Basel II framework, better repr...

Indicating shortcomings in surgical lighting systems.

Ergonomic problems of surgical lighting systems have been indicated by surgeons; however, the underlying causes are not clear. The aim of this study is to assess the problems in detail. Luminaire use during 46 hours of surgery was observed and quantified. Furthermore, a questionnaire on perceived illumination of and usability problems with surgical luminaires was issued among OR-staff in 13 hos...

Shortcomings of peer review in biomedical journals